Cystic ovary disease

Veterinary advice should be sought before applying any treatment or vaccine.

Cystic Ovary Disease

Cystic Follicles, “Bulling”

Cystic ovary disease (COD) is most commonly found in the ovary of dairy cows. It presents in two different forms; follicular or luteal cysts. Follicular cysts are soft and can be easily popped upon palpation of the rectum. Luteal cysts are thicker and more rubbery feel upon palpation.


Thick, crusty neck
Abrupt changes in milk production
Little to no muscle tone in the vulva, vagina and uterus
Elevated tail head


  • History
  • Clinical signs
  • Physical exam
  • Ultrasound


Treatment TypeDetailsReference
Hormone therapy with GnRH
LH-type hormonal treatment
luteolytic doses of PGF2α

Article Reference

Risk Factors

  • Feeding cows feed ingredients containing isoflavones or phytoestrogens
  • Allowing cows to consume red clover, whole soybeans or moldy feed
  • Administering exogenous estrogens and progestine to cattle

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