Locoweeds are perennial herbaceous plants composed of Astragalus spp. and Oxytropis spp. known for poisoning livestock. Locoweeds are toxic in all stages of growth, and whether it is fresh or dried. They both contain swainsonine, a toxic indolizidine alkaloid. Swainsonine is produced by fungal endophytes that contaminate locoweeds.
In addition to alkaloids, locoweeds can also accumulate excessive concentrations of selenium. Symptoms are usually seen after consumption of large amounts for 2 to 9 weeks. Signs last for several weeks. Young animals are most susceptible. Occasionally horses can recover however it is generally thrifty and will eat locoweed to the exclusion of other forage if returned to infested pasture.
Locoweeds are a large concern for ruminants living in the rangelands of the western United States, Asia, and South America. Consumption of locoweeds causes display behavioral disorders, gait abnormalities, and neurological symptoms such as ataxia, difficulty standing, standing abnormally, and leg paresis.
- Abnormal Behavior
- Infertility
- Abortion
- Heart Failure
- Weight Loss
- Poor Performance
- Depression
- Circling
- Incoordination
- Staggering Gait
- Difficult To Handle And Unpredictable
CHEMICAL CONTROL: Locoweed can be controlled by spraying actively growing or budding plants with clopyralid (20-30 gm ae/Ac), picloram (250 gm ai/Ac), and metsulfuron (30 gm ai/Ac). If plants are scattered, treatment of individual plants or patches may be practical.
- Cook, Daniel, et al. A swainsonine survey of North American Astragalus and Oxytropis taxa implicated as locoweeds Toxicon. 2016.
- D Knoke, D Giblin. Astragalus lentiginosus Burke Museum of Natural History and Culture. 2015.
- Early Detection & Distribution Mapping System Available online at http://www.eddmaps.org/; last accessed August 5, 2014. The University of Georgia - Center for Invasive Species and Ecosystem Health.. 2014.
- Identification And Treatment Of Locoweed – Tips On Controlling Locoweed Gardening Know-How. 2014.
- Zhao M, Gao X, Wang J, He X, Han B. A review of the most economically important poisonous plants to the livestock industry on temperate grasslands of China Journal of Applied Toxicology. 2013.
- United States Department of Agriculture (USDA) Plants Poisonous to Livestock in the Western States Agriculture Information Bulletin Number 415. 2011.
- Shao S, Zheng B The biogeochemistry of selenium in Sunan grassland, Gansu, Northwest China, casts doubt on the belief that Marco Polo reported selenosis for the first time in history Environ Geochem Health. 2008.
- Pfister JA, Stegelmeier BL, Cheney CD, Gardner DR. Effect of previous locoweed (Astragalus and Oxytropis species) intoxication on conditioned taste aversions in horses and sheep. Journal of Animal Science. 2007.
- Pfister JA, Stegelmeier BL, Gardner DR, James LF. Grazing of spotted locoweed (Astragalus lentiginosus) by cattle and horses in Arizona Journal of Animal Science. 2003.
- Pfister JA, Stegelmeier BL, Cheney CD, Ralphs MH, Gardner DR. Conditioning taste aversions to locoweed (Oxytropis sericea) in horses. Journal of Animal Science. 2002.
- Walkley SU, James LF. Locoweed-induced neuronal storage disease characterized by meganeurite formation Brain Research. 1984.